Dr. Juli Unternaehrer is Assistant Professor in the Department of Basic Sciences, Division of Biochemistry at
Loma Linda University School of Medicine. Her research activities are focused on cell fate choices in mammalian development and cancer.
During development, transcription factors and microRNAs both provide input to direct gene expression and determine lineage decisions.
Transcription factors controlling epithelial-mesenchymal transition are important both during development and in metastasis. MicroRNAs are
critical for control of gene expression and thus cell fate decisions and are often involved in temporal switches in lineage decisions. These
two classes of developmental regulators have been shown to influence one another, but their mutual regulatory functions are not completely
understood. She will use tissue culture and mouse models to study the interplay between EMT factors and microRNAs in development and cancer,
and syngeneic, xenograft, and induced pluripotent stem cell models of ovarian cancer to study disease onset and progression.